Identification of differential microRNAs and messenger RNAs resulting from ASXL transcriptional regulator 3 knockdown during during heart development

Congenital heart disease (CHD) is the most common birth defect. Although ASXL transcriptional regulator 3 (ASXL3) has been reported to cause hereditary CHD, ASXL3-mediated mechanisms in heart development remain unclear. In this study, we used dimethyl sulfoxide (DMSO) to induce differentiation in P1...

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Detalhes bibliográficos
Main Authors: Ze-Qun Liu, Mi Cheng, Fang Fu, Ru Li, Jin Han, Xin Yang, Qiong Deng, Lu-Shan Li, Ting-Ying Lei, Dong-Zhi Li, Can Liao
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2022-04-01
Colecção:Bioengineered
Assuntos:
ASXL transcriptional regulator 3
heart development
microRNA
messenger RNA
PI3K-akt
Acesso em linha:https://www.tandfonline.com/doi/10.1080/21655979.2022.2062525
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