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Design, Synthesis, and Antitumor Activity of Erlotinib Derivatives
Nineteen erlotinib derivatives bearing different 1,2,3-triazole moieties were designed, synthesized, and evaluated for their potential against different cancer cell lines. The structures of the synthesized compounds were confirmed via1H NMR, 13C NMR, and HR MS. Preliminary antitumor activity assay r...
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Главные авторы: | , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Frontiers Media S.A.
2022-04-01
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Серии: | Frontiers in Pharmacology |
Предметы: | |
Online-ссылка: | https://www.frontiersin.org/articles/10.3389/fphar.2022.849364/full |
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