Inhibition of Sox2 Expression in the Adult Neural Stem Cell Niche In Vivo by Monocationic-based siRNA Delivery

RNA interference (RNAi) is a major tool for basic and applied investigations. However, obtaining RNAi data that have physiological significance requires investigation of regulations and therapeutic strategies in appropriate in vivo settings. To examine in vivo gene regulation and protein function in...

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Bibliographic Details
Main Authors: Sylvie Remaud, Silvia Alejandra López-Juárez, Anne-Laure Bolcato-Bellemin, Patrick Neuberg, Fabrice Stock, Marie-Elise Bonnet, Rym Ghaddab, Marie Stéphanie Clerget-Froidevaux, Jacqueline Pierre-Simons, Patrick Erbacher, Barbara A Demeneix, Ghislaine Morvan-Dubois
Format: Artigo
Language:Inglês
Published: Elsevier 2013-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
adult neural stem cells
in vivo
monocationic lipid vector
non-viral transfection
siRNA
Sox2
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116301482
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