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A LigA three-domain region protects hamsters from lethal infection by Leptospira interrogans.
The leptospiral LigA protein consists of 13 bacterial immunoglobulin-like (Big) domains and is the only purified recombinant subunit vaccine that has been demonstrated to protect against lethal challenge by a clinical isolate of Leptospira interrogans in the hamster model of leptospirosis. We determ...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2011-12-01
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| Edice: | PLoS Neglected Tropical Diseases |
| On-line přístup: | http://europepmc.org/articles/PMC3236721?pdf=render |
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