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A LigA three-domain region protects hamsters from lethal infection by Leptospira interrogans.
The leptospiral LigA protein consists of 13 bacterial immunoglobulin-like (Big) domains and is the only purified recombinant subunit vaccine that has been demonstrated to protect against lethal challenge by a clinical isolate of Leptospira interrogans in the hamster model of leptospirosis. We determ...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science (PLoS)
2011-12-01
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| シリーズ: | PLoS Neglected Tropical Diseases |
| オンライン･アクセス: | http://europepmc.org/articles/PMC3236721?pdf=render |
| タグ: |
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