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Whole-genome analysis of papillary kidney cancer finds significant noncoding alterations.

To date, studies on papillary renal-cell carcinoma (pRCC) have largely focused on coding alterations in traditional drivers, particularly the tyrosine-kinase, Met. However, for a significant fraction of tumors, researchers have been unable to determine a clear molecular etiology. To address this, we...

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Detalhes bibliográficos
Main Authors: Shantao Li, Brian M Shuch, Mark B Gerstein
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2017-03-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC5391127?pdf=render
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