Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway

Baicalein, a widely-distributed natural flavonoid, exhibits antioxidative activity in mice with type-2 diabetes. However, the underlying mechanisms remain partially elucidated. In this study, we investigated the effect of baicalein on protein kinase R-like ER kinase (PERK)/nuclear factor erythroid-2...

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Bibliografiset tiedot
Päätekijät: Yuesheng Dong, Yan Xing, Jin Sun, Wenlong Sun, Yongbin Xu, Chunshan Quan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2020-01-01
Sarja:Molecules
Aiheet:
diabetes mellitus
baicalein
oxidative stress
apoptosis
liver
perk/nrf2 signaling pathway
Linkit:https://www.mdpi.com/1420-3049/25/3/599
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