Noradrenaline Acting on Alpha1 Adrenoceptor as well as by Chelating Iron Reduces Oxidative Burden on the Brain: Implications With Rapid Eye Movement Sleep

The noradrenaline (NA) level in the brain is reduced during rapid eye movement sleep (REMS). However, upon REMS deprivation (REMSD) its level is elevated, which induces apoptosis and the degeneration of neurons in the brain. In contrast, isolated studies have reported that NA possesses an anti-oxida...

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Hlavní autoři: Abhishek Singh, Gitanjali Das, Manjeet Kaur, Birendra N. Mallick
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019-02-01
Edice:Frontiers in Molecular Neuroscience
Témata:
catecholamine
C6
cell death
lipid peroxidation
oxidative stress
synaptosome
On-line přístup:https://www.frontiersin.org/article/10.3389/fnmol.2019.00007/full
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