Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides

Enzymatic synthesis is an elegant biocompatible approach to complex compounds such as human milk oligosaccharides (HMOs). These compounds are vital for healthy neonatal development with a positive impact on the immune system. Although HMOs may be prepared by glycosyltransferases, this pathway is oft...

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Autori principali: Pavlína Nekvasilová, Michaela Hovorková, Zuzana Mészáros, Lucie Petrásková, Helena Pelantová, Vladimír Křen, Kristýna Slámová, Pavla Bojarová
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-04-01
Serie:International Journal of Molecular Sciences
Soggetti:
enzymatic synthesis
glycosidase
human milk oligosaccharide
mutagenesis
Accesso online:https://www.mdpi.com/1422-0067/23/8/4106
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