Global expression profiling of CD10 + /CD19 + pre-B lymphoblasts from Hispanic B-ALL patients correlates with comparative TARGET database analysis

Abstract Mexico City has one of the highest incidences of acute lymphoblastic leukemia (ALL) globally, with patients showing low survival, and high relapse rates. To gain more insight into the molecular features of B-ALL in Mexican children, we isolated CD10 + /CD19 + precursor B lymphoblasts from f...

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Main Authors: Laura Castañeda-Partida, Rodolfo Ocadiz-Delgado, José Manuel Sánchez-López, Enrique García-Villa, José Gabriel Peñaloza-González, Martha Margarita Velázquez-Aviña, José Refugio Torres-Nava, Jorge Alfonso Martín-Trejo, Karina Solís-Labastida, Francisco Xavier Guerra-Castillo, Vilma Carolina Bekker-Méndez, Víctor Hugo Rosales-García, Dámaris Romero-Rodríguez, Raúl Mojica-Espinoza, Alfonso Mendez-Tenorio, Crystel A. Ramírez-Calzada, Elízabeth Álvarez-Ríos, Juan Manuel Mejía-Aranguré, Patricio Gariglio
Format: Artigo
Language:Inglês
Published: Springer 2022-04-01
Series:Discover Oncology
Subjects:
ARACNE
FACS
TARGET
Pediatric precursor B-ALL
PIK3CG
SMIM10LB2
Online Access:https://doi.org/10.1007/s12672-022-00480-7
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