Fluoroquinolone Resistance Mechanisms in an Escherichia coli Isolate, HUE1, Without Quinolone Resistance-Determining Region Mutations

Fluoroquinolone resistance can cause major clinical problems. Here, we investigated fluoroquinolone resistance mechanisms in a clinical Escherichia coli isolate, HUE1, which had no mutations quinolone resistance-determining regions (QRDRs) of DNA gyrase and topoisomerase IV. HUE1 demonstrated MICs t...

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Detalhes bibliográficos
Main Authors: Toyotaka eSato, Shin-ichi eYokota, Ikuo eUchida, Torahiko eOkubo, Masaru eUsui, Masahiro eKusumoto, Masato eAkiba, Nobuhiro eFujii, Yutaka eTamura
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013-05-01
Colecção:Frontiers in Microbiology
Assuntos:
Escherichia coli
efflux pump
Fluoroquinolone resistance
oqxAB
qnrS
AcrAB
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00125/full
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