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Wnt3a induces myofibroblast differentiation by upregulating TGF-β signaling through SMAD2 in a β-catenin-dependent manner.

Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However, the role of the Wnt pathway in such settings remains unclear. In the current study, we treated mo...

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Main Authors: Jon M Carthy, Farshid S Garmaroudi, Zongshu Luo, Bruce M McManus
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2011-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC3097192?pdf=render
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