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Gli activity is critical at multiple stages of embryonic mammary and nipple development.

Gli3 is a transcriptional regulator of Hedgehog (Hh) signaling that functions as a repressor (Gli3(R)) or activator (Gli3(A)) depending upon cellular context. Previously, we have shown that Gli3(R) is required for the formation of mammary placodes #3 and #5. Here, we report that this early loss of G...

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Bibliografske podrobnosti
Main Authors: Anupama Chandramouli, Sarah J Hatsell, Alicia Pinderhughes, Lisa Koetz, Pamela Cowin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2013-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3832531?pdf=render
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