Apoptotic machinery diversity in Multiple Myeloma molecular subtypes.

Multiple myeloma (MM) is a plasma cell malignancy that is heterogeneous in its clinical presentation and prognosis. Monoclonal gammopathy of undetermined significance (MGUS) consistently preceded development of MM. The presence of primary IgH translocations and the universal over-expression of cycli...

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Detalles Bibliográficos
Main Authors: Patricia eGomez-Bougie, Martine eAmiot
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Assuntos:
Multiple Myeloma
Plasma Cells
BCL-2 Family
MGUS
Molecular myeloma subgroups
Acceso en liña:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00467/full
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