Evidence for an Adaptation of a Phage-Derived Holin/Endolysin System to Toxin Transport in Clostridioides difficile

The pathogenicity locus (PaLoc) of Clostridioides difficile usually comprises five genes (tcdR, tcdB, tcdE, tcdA, tcdC). While the proteins TcdA and TcdB represent the main toxins of this pathogen, TcdR and TcdC are involved in the regulation of their production. TcdE is a holin family protein, memb...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Denise Mehner-Breitfeld, Claudia Rathmann, Thomas Riedel, Ingo Just, Ralf Gerhard, Jörg Overmann, Thomas Brüser
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018-10-01
Serija:Frontiers in Microbiology
Teme:
Clostridioides difficile
toxins
holins
endolysins
protein transport
Online dostop:https://www.frontiersin.org/article/10.3389/fmicb.2018.02446/full
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki