Comparative Stability of Two Anti-hyperpigmentation Agents: Kojic Acid as a Natural Metabolite and Its Di-Palmitate Ester, Under Oxidative Stress; Application to Pharmaceutical Formulation Design

Purpose: Kojic acid (KA) a natural metabolite and its dipalmitate ester, kojic acid dipalmitate(Kadp) are both prescribed to treat skin hyperpigmentation. Stress test reveals the intrinsicstability of active ingredients and leads to selection of the suitable formulations. This researchevaluates the...

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Détails bibliographiques
Auteurs principaux: Sahar Tazesh, Elnaz Tamizi, Mohammadreza Siahi Shadbad, Nazli Mostaghimi, Farnaz Monajjemzadeh
Format: Artigo
Langue:Inglês
Publié: Tabriz University of Medical Sciences 2022-03-01
Collection:Advanced Pharmaceutical Bulletin
Sujets:
stress test
oxidative stress
pharmaceutical preformulation
hplc
kinetic
degradation mechanism
Accès en ligne:https://apb.tbzmed.ac.ir/PDF/apb-12-329.pdf
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