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ROLE OF MORPHOLOGICAL AND GENETIC STRUCTURAL CHARACTERISTICS OF ESTROGEN RECEPTOR ALPHA IN THE DEVELOPMENT OF RESISTANCE TO ENDOCRINOTHERAPY WITH TAMOXIFEN IN PATIENTS WITH LUMINAL BREAST CANCER
Hormone therapy with tamoxifen is the commonly used treatment for luminal breast cancer. However, it appears to be ineffective in 20–40 % of cases and the possible reasons of this failure are related to the features of distribution and structure of estrogen receptor alpha (ERα) in tumor tissue. Real...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Russo |
| Izdano: |
Tomsk National Research Medical Center of the Russian Academy of Sciences
2016-02-01
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| Serija: | Sibirskij Onkologičeskij Žurnal |
| Teme: | |
| Online pristup: | https://www.siboncoj.ru/jour/article/view/50 |
| Oznake: |
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