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Identification of POMC exonic variants associated with substance dependence and body mass index.

Risk of substance dependence (SD) and obesity has been linked to the function of melanocortin peptides encoded by the proopiomelanocortin gene (POMC).POMC exons were Sanger sequenced in 280 African Americans (AAs) and 308 European Americans (EAs). Among them, 311 (167 AAs and 114 EAs) were affected...

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Detalhes bibliográficos
Main Authors: Fan Wang, Joel Gelernter, Henry R Kranzler, Huiping Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3444488?pdf=render
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