Plasma matrix metalloproteinases are associated with incident cardiovascular disease and all-cause mortality in patients with type 1 diabetes: a 12-year follow-up study

Abstract Background Altered regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to vascular complications in type 1 diabetes. We investigated associations between plasma MMP-1, -2, -3, -9, -10 and TIMP-1, a...

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Main Authors: S. A. Peeters, L. Engelen, J. Buijs, A. Jorsal, H.-H. Parving, L. Tarnow, P. Rossing, C. G. Schalkwijk, C. D. A. Stehouwer
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-04-01
Colecção:Cardiovascular Diabetology
Assuntos:
Type 1 diabetes
Cardiovascular disease
All-cause mortality
Matrix metalloproteinase
Tissue inhibitor of metalloproteinase
Estimated glomerular filtration rate
Acesso em linha:http://link.springer.com/article/10.1186/s12933-017-0539-1
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