Genotyping of Circulating Free DNA Enables Monitoring of Tumor Dynamics in Synovial Sarcomas

Background: Synovial sarcoma (SS) is a malignant soft tissue tumor of mesenchymal origin that frequently occurs in young adults. Translocation of the SYT gene on chromosome 18 to the SSX genes on chromosome X leads to the formation of oncogenic fusion genes, which lead to initiation and proliferatio...

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Detalhes bibliográficos
Main Authors: Anja E. Eisenhardt, Zacharias Brugger, Ute Lausch, Jurij Kiefer, Johannes Zeller, Alexander Runkel, Adrian Schmid, Peter Bronsert, Julius Wehrle, Andreas Leithner, Bernadette Liegl-Atzwanger, Riccardo E. Giunta, Steffen U. Eisenhardt, David Braig
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:Cancers
Assuntos:
soft tissue sarcoma
synovial sarcoma
next-generation sequencing
targeted sequencing
circulating tumor DNA
ctDNA
Acesso em linha:https://www.mdpi.com/2072-6694/14/9/2078
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