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Inhibition of RNA polymerase III transcription by Triptolide attenuates colorectal tumorigenesis
Abstract Background Upregulation of RNA polymerase (Pol) III products, including tRNAs and 5S rRNA, in tumor cells leads to enhanced protein synthesis and tumor formation, making it a potential target for cancer treatment. In this study, we evaluated the inhibition of Pol III transcription by tripto...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2019-05-01
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| Col·lecció: | Journal of Experimental & Clinical Cancer Research |
| Matèries: | |
| Accés en línia: | http://link.springer.com/article/10.1186/s13046-019-1232-x |
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