Can Biomarker Assessment on Circulating Tumor Cells Help Direct Therapy in Metastatic Breast Cancer?

Circulating tumor cell (CTC) count has prognostic significance in metastatic breast cancer, but the predictive utility of CTCs is uncertain. Molecular studies on CTCs have often been limited by a low number of CTCs isolated from a high background of leukocytes. Improved enrichment techniques are now...

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Detalles Bibliográficos
Main Authors: Natalie Turner, Marta Pestrin, Francesca Galardi, Francesca De Luca, Luca Malorni, Angelo Di Leo
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2014-03-01
Series:Cancers
Assuntos:
biomarker
breast cancer
CellSearch
chemotherapy
circulating tumor cells
HER2
liquid biopsy
metastatic
predictive biomarker
anti-HER2 therapy
Acceso en liña:http://www.mdpi.com/2072-6694/6/2/684
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