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Phase variation of a signal transduction system controls Clostridioides difficile colony morphology, motility, and virulence.
Recent work has revealed that Clostridioides difficile, a major cause of nosocomial diarrheal disease, exhibits phenotypic heterogeneity within a clonal population as a result of phase variation. Many C. difficile strains representing multiple ribotypes develop two colony morphotypes, termed rough a...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science (PLoS)
2019-10-01
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Colecção: | PLoS Biology |
Acesso em linha: | https://doi.org/10.1371/journal.pbio.3000379 |
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