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Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5.

The stalling of RNA polymerase II (RNAPII) at the promoters of many genes, including developmental regulators, stress-responsive genes, and HIVLTR, suggests transcription elongation as a critical regulatory step in addition to initiation. Spt5, the large subunit of the DRB sensitivity-inducing facto...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Hui Chen, Xavier Contreras, Yuki Yamaguchi, Hiroshi Handa, B Matija Peterlin, Su Guo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2009-09-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC2735033?pdf=render
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