Cell-in-cell structure mediates in-cell killing suppressed by CD44

Abstract Penetration of immune cells into tumor cells was believed to be immune-suppressive via cell-in-cell (CIC) mediated death of the internalized immune cells. We unexpectedly found that CIC formation largely led to the death of the host tumor cells, but not the internalized immune cells, manife...

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Detalhes bibliográficos
Main Authors: Yan Su, Hongyan Huang, Tianzhi Luo, You Zheng, Jie Fan, He Ren, Meng Tang, Zubiao Niu, Chenxi Wang, Yuqi Wang, Zhengrong Zhang, Jianqing Liang, Banzhan Ruan, Lihua Gao, Zhaolie Chen, Gerry Melino, Xiaoning Wang, Qiang Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2022-04-01
Colecção:Cell Discovery
Acesso em linha:https://doi.org/10.1038/s41421-022-00387-1
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