Transferrin Receptor 1 Regulates Thermogenic Capacity and Cell Fate in Brown/Beige Adipocytes

Abstract Iron homeostasis is essential for maintaining cellular function in a wide range of cell types. However, whether iron affects the thermogenic properties of adipocytes is currently unknown. Using integrative analyses of multi‐omics data, transferrin receptor 1 (Tfr1) is identified as a candid...

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Main Authors: Jin Li, Xiaohan Pan, Guihua Pan, Zijun Song, Yao He, Susu Zhang, Xueru Ye, Xiang Yang, Enjun Xie, Xinhui Wang, Xudong Mai, Xiangju Yin, Biyao Tang, Xuan Shu, Pengyu Chen, Xiaoshuang Dai, Ye Tian, Liheng Yao, Mulan Han, Guohuan Xu, Huijie Zhang, Jia Sun, Hong Chen, Fudi Wang, Junxia Min, Liwei Xie
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-06-01
Colecção:Advanced Science
Assuntos:
beigeing
brown fat determination
HIF1α
thermogenesis
transferrin receptor 1
Acesso em linha:https://doi.org/10.1002/advs.201903366
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