3DCoop: An approach for computational inference of cell-type-specific transcriptional regulators cooperation in 3D chromatin

Summary: Precise identification of context-specific transcriptional regulators (TRs) cooperation facilitates the understanding of complex gene regulation. However, previous methods are highly reliant on the availability of ChIPped TRs. Here, we provide a protocol for running 3DCoop, a pipeline for c...

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Bibliographic Details
Main Authors: Xianfu Yi, Menghan Luo, Xiangling Feng, Yao Zhou, Jianhua Wang, Mulin Jun Li
Format: Artigo
Language:Inglês
Published: Elsevier 2022-06-01
Series:STAR Protocols
Subjects:
Bioinformatics
Genetics
Genomics
Gene Expression
Systems biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722002623
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