Five novel PRNP gene polymorphisms and their potential effect on Scrapie susceptibility in three native Ethiopian sheep breeds

Abstract Background Classical scrapie susceptibility in sheep has been linked to three polymorphisms at codon 136, 154, and 171 in the prion protein gene (PRNP) whereas atypical scrapie susceptibility is related to polymorphisms at codon 141. Many other variants over the length of the PRNP have been...

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Autori principali: Eden Yitna Teferedegn, Yalcin Yaman, Cemal Un
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-04-01
Serie:BMC Veterinary Research
Soggetti:
Ethiopian sheep
Novel variations
Polymorphism
Prion gene
Scrapie susceptibility
Accesso online:http://link.springer.com/article/10.1186/s12917-020-02336-0
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