Permissivity of primary human hepatocytes and different hepatoma cell lines to cell culture adapted hepatitis C virus.

Significant progress has been made in Hepatitis C virus (HCV) culture since the JFH1 strain cloning. However, developing efficient and physiologically relevant culture systems for all viral genotypes remains an important goal. In this work, we aimed at producing a high titer JFH1 derived virus to te...

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Main Authors: Francois Helle, Etienne Brochot, Carole Fournier, Véronique Descamps, Laure Izquierdo, Thomas W Hoffmann, Virginie Morel, Yves-Edouard Herpe, Abderrahmane Bengrine, Sandrine Belouzard, Czeslaw Wychowski, Jean Dubuisson, Catherine Francois, Jean-Marc Regimbeau, Sandrine Castelain, Gilles Duverlie
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3734273?pdf=render
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