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Epigenetic Regulation of Host Defense Peptide Synthesis: Synergy Between Histone Deacetylase Inhibitors and DNA/Histone Methyltransferase Inhibitors
Host defense peptides (HDPs) are an integral part of the innate immune system acting as the first line of defense. Modulation of HDP synthesis has emerged as a promising host-directed approach to fight against infections. Inhibition of histone deacetylation or DNA methylation is known to enhance HDP...
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Main Authors: | , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Frontiers Media S.A.
2022-04-01
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Sraith: | Frontiers in Immunology |
Ábhair: | |
Rochtain Ar Líne: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.874706/full |
Clibeanna: |
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