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RNA-activated protein kinase differentially modulates innate immune response mediated by supraphysiological concentrations of thyroid hormone

Nuclear hormone receptor ligands are known to modulate innate immunity by dampening the immune response induced by pathogens. Here, we report that unlike other ligands, 3,3′,5-triiodo- l -thyronine (T3) induced the type 1 IFN response and expression of IFN-stimulated genes (ISGs). T3 action was foun...

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Detalhes bibliográficos
Main Authors: Mohammad Ishaq, Ven Natarajan
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2020-11-01
Colecção:Innate Immunity
Acesso em linha:https://doi.org/10.1177/1753425920955214
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