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Peripheral Dopamine Controlled by Gut Microbes Inhibits Invariant Natural Killer T Cell-Mediated Hepatitis
Neurotransmitters have been shown to regulate immune responses, and thereby are critically related to autoimmune diseases. Here we showed that depletion of dopaminergic neurons significantly promoted activation of hepatic iNKT cells and augmented concanavalin A (Con A)-induced liver injury. The supp...
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Главные авторы: | , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Frontiers Media S.A.
2018-10-01
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Серии: | Frontiers in Immunology |
Предметы: | |
Online-ссылка: | https://www.frontiersin.org/article/10.3389/fimmu.2018.02398/full |
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