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Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1
We have previously shown that high expression of the nucleic acid binding factor YB-1 is strongly associated with poor prognosis in a variety of cancer types. The 3-dimensional protein structure of YB-1 has yet to be determined and its role in transcriptional regulation remains elusive. Drug targeti...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2019-09-01
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Colecção: | Acta Pharmaceutica Sinica B |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2211383518310050 |
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