CHRNA4 rs1044396 is associated with smoking cessation in varenicline therapy

The large individual variability in response to drugs for smoking cessation suggests that specific treatments can be more effective in particular subgroups of smokers. In the context of personalized medicine, the main aim of the present study was to evaluate whether the CHRNA4 and CHRNB2 polymorphis...

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Main Authors: Juliana Rocha Santos, Paulo Roberto Xavier Tomaz, Jaqueline Scholz Issa, Tania Ogawa Abe, Jose Eduardo Krieger, Alexandre Costa Pereira, Paulo C J L Santos
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Genetics
Assuntos:
Smoking Cessation
varenicline
pharmacogenetic
polymorphism
CHRNA4
CHRNB2
Acceso en liña:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00046/full
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