Single-cell landscape of immunocytes in patients with extrahepatic cholangiocarcinoma

Abstract Background The intricate landscape of immunocytes in the tumor microenvironment (TME) is fundamental to immunotherapy but notably under-researched in extrahepatic cholangiocarcinoma (ECCA). Methods Single-cell RNA sequencing technology was conducted to make an in-depth analysis of immunocyt...

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Hlavní autoři: Lei Xu, Yun Lu, Zhengdong Deng, Xiangyu Li, Yuanxin Shi, Kai Zhao, Wei Yao, Jianming Wang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2022-05-01
Edice:Journal of Translational Medicine
Témata:
Extrahepatic cholangiocarcinoma
Immunocyte
Single-cell RNA sequencing
Tumor heterogeneity
Cellular interactions
On-line přístup:https://doi.org/10.1186/s12967-022-03424-5
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