Erroneous energy-generating cycles in published genome scale metabolic networks: Identification and removal.

Energy metabolism is central to cellular biology. Thus, genome-scale models of heterotrophic unicellular species must account appropriately for the utilization of external nutrients to synthesize energy metabolites such as ATP. However, metabolic models designed for flux-balance analysis (FBA) may c...

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Bibliographic Details
Main Authors: Claus Jonathan Fritzemeier, Daniel Hartleb, Balázs Szappanos, Balázs Papp, Martin J Lercher
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2017-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5413070?pdf=render
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