Periostin Contributes to the Pathogenesis of Atopic Dermatitis by Inducing TSLP Production from Keratinocytes

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease where Th2-type immune responses are dominant. Keratinocytes persistently secrete proinflammatory cytokines and chemokines, amplifying Th2-type responses in AD. We have recently reported that periostin, an extracellular matrix...

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Detalhes bibliográficos
Main Authors: Hiroshi Shiraishi, Miho Masuoka, Shoichiro Ohta, Shoichi Suzuki, Kazuhiko Arima, Kazuto Taniguchi, Shigehisa Aoki, Shuji Toda, Tomohiro Yoshimoto, Naoki Inagaki, Simon J Conway, Yutaka Narisawa, Kenji Izuhara
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012-01-01
Colecção:Allergology International
Assuntos:
atopic dermatitis
house dust mite
periostin
Th2 cells
TSLP
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1323893015302574
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