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The TRiCky Business of Protein Folding in Health and Disease

Maintenance of the cellular proteome or proteostasis is an essential process that when deregulated leads to diseases like neurological disorders and cancer. Central to proteostasis are the molecular chaperones that fold proteins into functional 3-dimensional (3D) shapes and prevent protein aggregati...

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Detalhes bibliográficos
Main Authors: Heba Ghozlan, Amanda Cox, Daniel Nierenberg, Stephen King, Annette R. Khaled
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Cell and Developmental Biology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2022.906530/full
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