Potential therapeutic molecular targets for blood-brain barrier disruption after subarachnoid hemorrhage

Aneurysmal subarachnoid hemorrhage remains serious hemorrhagic stroke with high morbidities and mortalities. Aneurysm rupture causes arterial bleeding-induced mechanical brain tissue injuries and elevated intracranial pressure, followed by global cerebral ischemia. Post-subarachnoid hemorrhage ische...

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Detalhes bibliográficos
Main Authors: Hideki Kanamaru, Hidenori Suzuki
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2019-01-01
Colecção:Neural Regeneration Research
Assuntos:
blood-brain barrier; early brain injury; endothelial cell; subarachnoid hemorrhage; tight junction; inflammation; matricellular protein; Toll-like receptor 4; TLR4
Acesso em linha:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=7;spage=1138;epage=1143;aulast=Kanamaru
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