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Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection
Cognitive dysfunction persists in 30–50% of chronically HIV-infected individuals despite combination antiretroviral therapy (ART). Although monocytes are implicated in poor cognitive performance, distinct biological mechanisms associated with cognitive dysfunction in HIV infection are unclear. We pr...
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Main Authors: | , , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Frontiers Media S.A.
2019-11-01
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Serier: | Frontiers in Immunology |
Fag: | |
Online adgang: | https://www.frontiersin.org/article/10.3389/fimmu.2019.02789/full |
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