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miRNA‐34c Suppresses Osteosarcoma Progression In Vivo by Targeting Notch and E2F
ABSTRACT The expression of microRNAs (miRNAs) is dysregulated in many types of cancers including osteosarcoma (OS) due to genetic and epigenetic alterations. Among these, miR‐34c, an effector of tumor suppressor P53 and an upstream negative regulator of Notch signaling in osteoblast differentiation,...
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Hauptverfasser: | , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Wiley
2022-05-01
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Schriftenreihe: | JBMR Plus |
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Online Zugang: | https://doi.org/10.1002/jbm4.10623 |
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