Multifunctional selenium nanoparticles with Galangin-induced HepG2 cell apoptosis through p38 and AKT signalling pathway

The morbidity and mortality of hepatocellular carcinoma, the most common cancer, are increasing continuously worldwide. Galangin (Ga) has been demonstrated to possess anti-cancer effect, but the efficacy of Ga was limited by its low permeability and poor solubility. To develop aqueous formulation an...

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Hlavní autoři: Yinghua Li, Min Guo, Zhengfang Lin, Mingqi Zhao, Yu Xia, Changbing Wang, Tiantian Xu, Bing Zhu
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2018-01-01
Edice:Royal Society Open Science
Témata:
selenium nanoparticles
galangin
caspase-3
reactive oxygen species
apoptosis
On-line přístup:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.180509
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