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COMMD1-mediated ubiquitination regulates CFTR trafficking.
The CFTR (cystic fibrosis transmembrane conductance regulator) protein is a large polytopic protein whose biogenesis is inefficient. To better understand the regulation of CFTR processing and trafficking, we conducted a genetic screen that identified COMMD1 as a new CFTR partner. COMMD1 is a protein...
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Autors principals: | , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Public Library of Science (PLoS)
2011-01-01
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Col·lecció: | PLoS ONE |
Accés en línia: | http://europepmc.org/articles/PMC3069076?pdf=render |
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