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R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells
Abstract Background As newly identified Wnt enhancer, R-spondin gene family members have been linked to various cancers; however, their role in isocitrate dehydrogenase-wildtype subtype of human glioblastoma (GBM) cells remains unknown. Methods Human U87 and U251 cell lines were used to perform the...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2018-10-01
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| Серии: | Cancer Cell International |
| Предметы: | |
| Online-ссылка: | http://link.springer.com/article/10.1186/s12935-018-0655-3 |
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