P6 ANGIOTENSIN AT2 RECEPTOR AGONIST, COMPOUND 21, MAINTAINS VASCULAR INTEGRITY AND PREVENTS ABDOMINAL AORTIC ANEURYSM PROGRESSION IN THE RAT

The effects of the selective angiotensin AT2 receptor agonist, compound 21 (C21), on abdominal aortic aneurysm (AAA) formation were investigated in normotensive Wistar rats. AAA was induced by perfusion of isolated aortic segments with elastase (Anidjar/Dobrin model). Treatment with C21 (0.03 and 0...

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Hauptverfasser: Christoph Lange, Manuela Sommerfeld, Pawel Namsolleck, Ulrich Kintscher, Thomas Unger, Elena Kaschina
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2017-12-01
Schriftenreihe:Artery Research
Online Zugang:https://www.atlantis-press.com/article/125930239/view
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