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Roflumilast in Severely Ill Patients with Chronic Obstructive Pulmonary Disease with Frequent Exacerbations: Risk of Pneumonia Hospitalization and Severe Exacerbations

Roflumilast is given as an add-on to inhalation medication in patients with chronic obstructive pulmonary disease (COPD) and chronic bronchitis. Animal experiments have documented deleterious effects of roflumilast in bacterial infections, but trials have not reported the risk of bacterial infection...

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Main Authors: Imane Achir Alispahic, Rikke Sørensen, Josefin Eklöf, Pradeesh Sivapalan, Anders Løkke, Niels Seersholm, Jakob Hedemark Vestergaard, Jens-Ulrik Stæhr Jensen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-05-01
Serier:Journal of Clinical Medicine
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Online adgang:https://www.mdpi.com/2077-0383/9/5/1442
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