Cisplatin resistance-related multi-omics differences and the establishment of machine learning models

Abstract Objectives Platinum-based chemotherapies are currently the first-line treatment of non-small cell lung cancer. This study will improve our understanding of the causes of resistance to cisplatin, especially in lung adenocarcinoma (LUAD) and provide a reference for therapeutic decisions in cl...

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Main Authors: Qihai Sui, Zhencong Chen, Zhengyang Hu, Yiwei Huang, Jiaqi Liang, Guoshu Bi, Yunyi Bian, Mengnan Zhao, Cheng Zhan, Zongwu Lin, Qun Wang, Lijie Tan
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMC 2022-04-01
Sraith:Journal of Translational Medicine
Ábhair:
Cisplatin
Drug resistance
Machine learning
IC50
Rochtain Ar Líne:https://doi.org/10.1186/s12967-022-03372-0
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