Imidazoline receptors in the heart: a novel target and a novel mechanism of action that involves atrial natriuretic peptides

Chronic stimulation of sympathetic nervous activity contributes to the development and maintenance of hypertension, leading to left ventricular hypertrophy (LVH), arrhythmias and cardiac death. Moxonidine, an imidazoline antihypertensive compound that preferentially activates imidazoline receptors i...

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Bibliographic Details
Main Authors: S. Mukaddam-Daher, J. Gutkowska
Format: Artigo
Language:Inglês
Published: Associação Brasileira de Divulgação Científica 2004-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Sympathetic nerve activity
Imidazoline receptors
Moxonidine
Atrial natriuretic peptide
Brain natriuretic peptide
Hypertension
Heart
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000800015
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