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Dual Inhibition of AChE and BChE with the C-5 Substituted Derivative of Meldrum’s Acid: Synthesis, Structure Elucidation, and Molecular Docking Studies

Alzheimer’s disease (AD) lies in the category of those diseases which are still posing challenges to medicinal chemists, and the search for super-effective drugs for the treatment of AD is a work in progress. The inhibition of cholinesterase is considered a viable strategy to enhance the level of ac...

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Main Authors: Haroon Mehfooz, Aamer Saeed, Anamika Sharma, Fernando Albericio, Fayaz Ali Larik, Farukh Jabeen, Pervaiz Ali Channar, Ulrich Flörke
格式: Artigo
語言:Inglês
出版: MDPI AG 2017-07-01
叢編:Crystals
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在線閱讀:https://www.mdpi.com/2073-4352/7/7/211
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