Genetic Variation in the 3'-Untranslated Region of NBN Gene Is Associated with Gastric Cancer Risk in a Chinese Population.

NBN plays a crucial role in carcinogenesis as a core component for both homologous recombination (HR) and non-homologous end-joining (NHEJ) DNA double-strand breaks (DSBs) repair pathways. Genetic variants in the NBN gene have been associated with multiple cancers risk, suggesting pleiotropic effect...

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Hauptverfasser: Ping Sun, Jiangbo Du, Xun Zhu, Chuanli Ren, Lan Xie, Ningbin Dai, Yayun Gu, Caiwang Yan, Juncheng Dai, Hongxia Ma, Yue Jiang, Jiaping Chen, Zhibin Hu, Hongbing Shen, Haorong Wu, Guangfu Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2015-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC4581712?pdf=render
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